Many studies using diffusion tensor tractography DTT have demonstrated that injury of the spinothalamic tract STT is the pathogenetic mechanism of central post-stroke pain CPSP in intracerebral hemorrhage; however, there is no DTT study reporting the pathogenetic mechanism of CPSP in cerebral infarction. Five patients with CPSP following cerebral infarction and eight age- and sex-matched healthy control subjects were recruited for this study. Among DTT parameters of the affected STT, fractional anisotropy and tract volume were decreased by more than two standard deviations in two patients patients 1 and 2 and three patients patients 3, 4, and 5 , respectively, compared with those of the control subjects, while mean diffusivity value was increased by more than two standard deviations in one patient patient 2. Users Online: J Mol Neurosci


Segmental hypersensitivity and spinothalamic function in spinal cord injury pain




Spinothalamic tracts | Radiology Reference Article | scudc.info
Metrics details. We report on a patient with a mild traumatic brain injury TBI who developed abdominal pain due to spinothalamic tract STT injuries revealed by diffusion tensor tractography DTT. A year-old female patient suffered head trauma resulting from a backward fall. While bathing at a public bathhouse, she fell backward and struck the occipital area of her head against the floor. After the head trauma, she experienced pain in the abdomen and in both hands and feet.



Incomplete Spinal Cord Injury
They are responsible for transmitting pain, temperature, coarse non-discriminative touch and pressure sensations 1. Unlike other tracts main spinal tracts, the spinothalamic tracts decussate in the spinal cord itself and account for the pattern of deficit encountered in cord hemisection Brown-Sequard syndrome. First-order neurons, whose cell bodies are in the dorsal root ganglion, and whose axons extend from peripheral receptors, synapse with second-order neurons located in the ipsilateral dorsal horn of the cord. The spinothalamic tract is divided into lateral and anterior tracts, which are discussed separately 1 :.





In its pure form, it is rarely seen. The most common cause is penetrating trauma such as a gunshot wound or stab wound to the spinal cord. The presentation can be progressive and incomplete. It is not always permanent and progression or resolution depends on the severity of the original spinal cord injury and the underlying pathology that caused it in the first place. The hemisection of the cord results in a lesion of each of the three main neural systems: [ citation needed ].

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